Introductory Statistics for the Life and Biomedical Sciences
First Edition available in full-color PDF and B&W paperback
Textbook Pedagogy
Introduction to Statistics for the Life and Biomedical Sciences has been written to be used in conjunction with a set of self-paced learning labs. These labs guide students through learning how to apply statistical ideas and concepts discussed in the text with the R computing language.
The text discusses the important ideas used to support an interpretation (such as the notion of a confidence interval), rather than the process of generating such material from data (such as computing a confidence interval for a particular subset of individuals in a study). This allows students whose main focus is understanding statistical concepts to not be distracted by the details of a particular software package. In our experience, however, we have found that many students enter a research setting after only a single course in statistics. These students benefit from a practical introduction to data analysis that incorporates the use of a statistical computing language.
In a classroom setting, we have found it beneficial for students to start working through the labs after having been exposed to the corresponding material in the text, either from self-reading or through an instructor presenting the main ideas. The labs are organized by chapter, and each lab corresponds to a particular section or set of sections in the text.
There are traditional exercises at the end of each chapter that do not require the use of computing. More complicated methods, such as multiple regression, do not lend themselves to hand calculation and computing is necessary for gaining practical experience with these methods. The lab exercises for these later chapters become an increasingly important part of mastering the material.
An essential component of the learning labs are the "Lab Notes" accompanying each chapter. The lab notes are a detailed reference guide to the R functions that appear in the labs, written to be accessible to a first-time user of a computing language. They provide more explanation than available in the R help documentation, with examples specific to what is demonstrated in the labs. The notes cover topics such as constructing histograms, writing loops, and running regression models.
Getting Started
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FREE -- Textbook PDF (1st Edition)
If you want to skip the optional contribution, set the price to $0
$25 -- B&W paperback
Available on Amazon and in select bookstores
Survival Analysis in R
Workshop materials and a guide for survival analysis in R
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List of known textbook typos
Review textbook typos and clarifications
For Teachers
Resources for teachers, some of which are restricted to Verified Teachers only. Slides, labs, and other resources may also be found in the corresponding chapter sections below.
Learn about Teacher Verification
Benefits, options to apply, and the verification process
Teachers page with additional resources
Some public resources, others restricted to Verified Teachers
Request a textbook desk copy (US only)
Available to Verified Teachers, click here to apply for access
Solutions for Intro Stat for the Life & Biom. Sci.
Available to Verified Teachers, click here to apply for access
LaTeX source files for the book
Leads to the Github repository
Sample Exams + Problem Sets
Access to exams and these supplemental problem sets are limited to Verified Teachers.
ISLBS, Sample Midterm and Final Exams (Julie Vu)
Available to Verified Teachers, click here to apply for access
ISLBS, Problem Sets (Julie Vu)
Available to Verified Teachers, click here to apply for access
What is Statistics?
These resources give a taste of what statisticians, also known as data scientists, do in the real world.
200 years of history through health & wealth
A tour with Hans Rosling
Bringing life to global health statistics
A longer tour led by Hans Rosling
Building a better NBA team through analytics
Ivana Seric, college basketball player becomes a data scientist
Steven Levitt explores the value of car seats
Disclaimers at the end
Using statistics to treat chronic illnesses
MacArthur Fellow Susan Murphy
Using data to better understand agriculture
MacArthur Fellow David Lobell
Why the term "Data Science" is so confusing
The two main types of data scientists: Analysis and Building
Chapter 1: Intro to Data
Lab - Intro to Data Labs
Software: R (Base)
Slides - Exploring Data
PDF + Rmarkdown slides are on Github
Chapter 2: Probability
Chapter 3: Distributions of Random Variables
Lab - Distributions of Random Variables Labs
Software: R (Base)
Slides - Distributions of Random Variables
PDF + Rmarkdown slides are on Github
Chapter 4: Foundations for Inference
Lab - Foundations for Inference Labs
Software: R (Base)
Slides - Introduction to Inference
PDF + Rmarkdown slides are on Github
Chapter 5: Inference for Numerical Data
Lab - Inference for Numerical Data Labs
Software: R (Base)
Slides - Inference for Numerical Data
PDF + Rmarkdown slides are on Github
Chapter 6: Simple Linear Regression
Lab - Simple Linear Regression Labs
Software: R (Base)
Slides - Simple Linear Regression
PDF + Rmarkdown slides are on Github
Chapter 7: Multiple Linear Regression
Lab - Multiple Linear Regression Labs
Software: R (Base)
Slides - Multiple Linear Regression
PDF + Rmarkdown slides are on Github
Chapter 8: Inference for Categorical Data
Lab - Inference for Categorical Data Labs
Software: R (Base)
Slides - Inference for Categorical Data
PDF + Rmarkdown slides are on Github
Additional Topics
Inference for Binary Data, Chapter 8 supplemental section
This supplement to the 1st Edition is being released online as an extension to Chapter 8. It provides additional detail about the properties of summary statistics for 2 x 2 tables, including risk, prevalence, and odds ratios.
Lab - Logistic Regression Labs
Software: R (Base)
Logistic Regression supplemental section
Source: OpenIntro Statistics, 4th Edition
Slides - Logistic Regression
PDF + Rmarkdown slides are on Github
Survival Analysis in R
Workshop materials and a guide for survival analysis in R
More Student Resources
More Free Books
Beyond the set of textbooks we offer on openintro.org, many other authors have made their books publicly available. The links below go to the places where these other authors posted their books for free for anyone.
Statistical Inference via Data Science
Paperbacks run about $75
A First Course in Design and Analysis of Experiments
Includes supplemental resources
An Introduction to Statistical Learning
Physical copies are about $80
Elements of Statistical Learning
Physical copies are about $90
Principles of Epidemiology in Public Health Practice
Print version at bookstore.phf.org for about $65
Survival Analysis in R
Workshop materials and a guide for survival analysis in R
Introduction to Probability
Physical copies are about $60
Practical Regression and ANOVA using R
Related publisher title: Linear Models with R
Think Stats
Physical copies are about $30
Collaborative Statistics on CNX.org
Physical copies are about $30 on Lulu
CK-12 Probability and Statistics
CK-12 offers many open-source textbooks
Introduction to Statistical Thought
Upper division or intro grad level
Introduction to Probability and Statistics Using R
Available on R-Forge
Online Statistics Education
An Interactive Multimedia Course of Study
Introduction to Statistical Thinking
With R, Without Calculus